Aim of the course:
The main purpose of the course is to introduce
fundamental and applied aspects of the problems concerning biocompatible
materials in biomedicine to students. The main focus of the course are aspects
of working with biomaterials as hydrophobic properties of various insoluble
biopolymers and obtaining biocompatible materials for regenerative medicine. As
part of the course, students will get familiarized with a set of methods for
obtaining bioresorbable films, scaffolds and microspheres with different surface
microstructure and porosity and learn about their mechanical properties.
Furthermore, the students will also get acquainted with methods for drug
loading of biopolymer structures and studying drug release in prolonged drug
delivery models.
Description:
The course of practical biotechnology presents five
practical tasks, as a result of which students will learn basic skills in the
laboratory, working under fume hood, working with polymers, and working with
volatile substances. They will learn how to plan the experiment, set up the
experiment themselves, and also learn to write reports in the form of small
abstracts. The course will include the following practical work: obtaining
polymer films and calculating hydrophobicity through the force of surface
tension; obtaining and studying polymer porous scaffolds; studying porous
polymer scaffolds in vitro; obtaining and studying polymer porous
microparticles; release control of drugs and polymer porous microparticles;
study of protein adsorption on polymer films and matrices.
Grading:
Work on seminars and written task reports.
- Преподаватель: AkoulinaElizaveta